Publications 

Selected publications:

Abdel-Razek O., Marzouk A., MacKinnon M., Guy E. T. 4th, Pohar S. A., Zhushma E., Liu J., Sia I., Gokey J. J., Tay H. G. and Amack J. D. (2023) Calcium signaling mediates proliferation of the precursor cells that give rise to the ciliated left-right organizer in the zebrafish embryo. Frontiers in Molecular Biosciences. Special Topic: Molecular mechanisms of cilia related diseases. Dec 12;10:1292076. doi: 10.3389/fmolb.2023.1292076.

Forrest K., Barricella A. C., Pohar S. A., Hinman A. M., Amack J. D. (2022) Understanding laterality disorders and the left-right organizer: Insights from zebrafish. Frontiers in Cell and Developmental Biology, Dec 23;10:1035513. doi: 10.3389/fcell.2022.1035513. Invited review.

Wang J., Thomas H. R., Thompson R. G., Waldrep S. C., Fogerty J., Song P., Li Z., Ma Y., Santra P., Hoover J. D., Yeo N. C., Drummond I. A., Yoder B. K., Amack J. D., Perkins B., Parant J. M. (2022) Variable phenotypes and penetrance between and within different zebrafish ciliary transition zone mutants. Disease Models and Mechanisms. Dec 1;15(12). doi: 10.1242/dmm.049568.

Amack J. D.  (2022) Structures and functions of cilia during vertebrate embryo development. Molecular Reproduction and Development, Nov. 11; doi: 10.1002/mrd.23650. Invited review.

Santra, P. and Amack J. D.  (2021) Loss of vacuolar-type H+-ATPase induces caspase-independent necrosis-like death of hair cells in zebrafish neuromasts. Disease Models and Mechanisms, Jul 1;14(7):dmm048997. Selected for Journal cover.

Sanematsu P. C., Erdemci-Tandogan G., Patel H., Retzlaff E. M., Amack J. D. and Manning M. L. (2021) 3D viscoelastic drag forces contribute to cell shape changes during organogensis in the zebrafish embryo. Cells and Development, Jul 14;203718. Special Topic: Quantitative Cell and Developmental Biology.

Amack J. D. (2021) Cellular dynamics of EMT: lessons from live in vivo imaging of embryonic development. Cell Communication and Signaling, Jul 22;19(1):79.  Invited review. Research Square Video Byte:  https://youtu.be/RgWSum2CqTE

Hoang P., Kowalczewski A., Sun S., Winston T. S., Archilla A. M., Lemus S. M., Ercan-Sencicek A. G., Gupta A. R., Liu W., Kontaridis M. I., Amack J. D. and Ma Z. (2021) Engineering spatial-organized cardiac organoids for developmental toxicity testing. Stem Cell Reports, May 11;16(5):1228-1244.

Rathbun L. I., Colicino E. G., Manikas J., O’Connell J., Krishnan N., Reilly N. S., Coyne S., Erdemci- Tandogan G., Garrastegui A., Freshour J., Santra P., Manning M. L., Amack J. D. and Hehnly H. (2020) Cytokinetic bridge triggers lumen formation in vivo. Nature Communications, Mar 9;11(1):1269.    

Colicino E. G., Stevens, K., Curtis E., Rathbun L., Bates M., Manikas J., Amack J. D., Freshour J. and Hehnly H. (2019) Chromosome misalignment is associated with PLK1 activity at cenexin-positive mitotic centrosomes. Molecular Biology of the Cell, Jun 15;30(13):1598-1609.

Erdemci-Tandogan G., Clark M. J., Amack J. D. and Manning M. L. (2018) Tissue flow induces cell shape changes during organogenesis. Biophysical Journal, Dec 4;115(11):2259-2270.

Dasgupta A., Merkel M., Clark M. J., Jacob A. E., Dawson J. E., Manning M. L. and Amack J. D. (2018) Cell volume changes contribute to epithelial morphogenesis in zebrafish Kupffer’s vesicle. eLife, Jan 29;7.

Saydmohammed M., Yagi, H., Calderon M., Clark M. J., Feinstein T., Sun M., Stolz D. B., Watkins S. C.,  Amack J. D., Lo C. W. and Tsang M. (2018) Vertebrate Myosin 1d regulates left-right organizer morphogenesis and laterality. Nature Communications, Aug 23;9(1):3381.

Jacob A. E., Amack J. D. and Turner C. E. (2017) Paxillin genes and actomyosin contracility regulate myotome morphogenesis in zebrafish. Developmental Biology, 425(1):70-84.

Dasgupta A. and Amack J. D. (2016) Cilia in vertebrate left-right patterning. Philosopical Transactions of the Royal Society of London Series B Biological Sciences, 19; 371(1710). Invited review.

Ji Y., Buel S. M. and Amack J. D. (2016) Mutations in zebrafish pitx2 model congenital malformations in Axenfeld-Rieger syndrome but do not disrupt left-right placement of visceral organs. Developmental Biology, 416(1):69-81.

Gokey J. J., Ji Y.,  Tay H. G., Litts B. and Amack J. D. (2016) A Kupffer’s vesicle size threshold for robust left-right patterning of the zebrafish embryo. Developmental Dynamics, 245(1):22-33.

Gokey J. J., Dasgupta A. and Amack J. D. (2015) The V-ATPase accessory protein Atp6ap1b mediates dorsal forerunner cell proliferation and left-right asymmetry in zebrafish. Developmental Biology, 407(1):115-30.

Fox C., Manning M. L. and Amack J. D. (2015) Quantitative description of fluid flows produced by left-right cilia in zebrafish. Methods in Cell Biology,127:175-87. Featured on Journal cover.

Jin D., Ni T. T., Sun J., Wan H., Amack J. D., Yu G., Fleming J., Chiang C., Li W., Papierniak A., Cheepala S., Conseil G., Cole S. P., Zhou B., Drummond I. A., Schuetz J. D., Malicki J. and Zhong T.P. (2014) Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport. Nature Cell Biology,16(9):841-51. 

Wang W. J., Tay H. G., Soni R., Perumal G. S., Goll M. G., Macaluso F. P., Asara J. M., Amack J. D. and Tsou M. F. (2013) CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base. Nature Cell Biology, 15:591-601.

Tay H. G., Schulze S. K., Compagnon J., Foley F. C., Heisenberg C. P., Yost H. J., Abdelilah-Seyfried S., and Amack J. D. (2013) Lethal giant larvae 2 regulates development of the ciliated organ Kupffer’s vesicle. Development, 140(7): 1550-9.

Amack J. D. and Manning M. L. (2012) Knowing the boundaries: extending the differential adhesion hypothesis in embryonic cell sorting. Science, 338(6104): 212-5.

Wang G., Manning M. L. and Amack J. D. (2012) Regional cell shape changes control form and function of Kupffer’s vesicle in the zebrafish embryo. Developmental Biology, 370(1): 52-62.

French V., van de Laar I., Wessels, M. W., Rohe, C., Roos-Hesselink, J. W., Frohn-Mulder, I., Severijnen, L., de Graaf, B. M., Wang G., Schot R., Breedveld G., Mientjes E., van Tienhoven M., Jadot E., Jiang Z., Verkerk A., Swagemakers S., Venselaar H., Rahimi Z., Najmabadi H., Meijers-Heijboer H., de Graaff E., Helbing W. A., Willemsen R., Devriendt K., Belmont J. W., Oostra B. A., Amack J. D. and Bertoli-Avella A. M. (2012) NPHP4 variants are associated with pleiotropic heart malformations. Circulation Research, 110(12): 1564-74. 

Wang G., Cadwallader A. B., Jang D. S., Tsang M., Yost H. J. and Amack J. D. (2011) The Rho kinase Rock2b establishes anteroposterior asymmetry of the ciliated Kupffer’s vesicle in zebrafish. Development, 138(1), 45-54. Selected for Journal cover. Featured in Development.

Neugebauer J. M., Amack J. D., Peterson, A. G., Bisgrove, B. W. and Yost H. J. (2009) FGF signalling during embryo development regulates cilia length in diverse epithelia. Nature, 458(7238), 651-4.

Essner J. J., Amack J. D., Nyholm M. K., Harris E. B. and Yost H. J. (2005) Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut. Development, 132 (6), 1247-60.

Amack J. D. and Yost H. J. (2004) The T box transcription factor no tail in ciliated cells controls zebrafish left-right asymmetry. Current Biology, 14(8), 685-90.


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